Current advances in using neurotrophic factors to treat neurodegenerative disorders

door Weissmiller, April M, Wu, Chengbiao
Gepubliceerd in 2012

Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects

door Rodrigues, Elizabeth M., Weissmiller, April M., Goldstein, Lawrence S.B.
Gepubliceerd in 2012

The MYC–WDR5 Nexus and Cancer

door Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Tansey, William P.
Gepubliceerd in Cancer Res (2015)

Targeting WDR5: A WINning Anti-Cancer Strategy?

door Aho, Erin R, Weissmiller, April M, Fesik, Stephen W, Tansey, William P
Gepubliceerd in Epigenet Insights (2019)

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons

door Zhao, Xiaobei, Zhou, Yue, Weissmiller, April M., Pearn, Matthew L., Mobley, William C., Wu, Chengbiao
Gepubliceerd in J Vis Exp (2014)

Inhibition of MYC by the SMARCB1 tumor suppressor

door Weissmiller, April M., Wang, Jing, Lorey, Shelly L., Howard, Gregory C., Martinez, Ernest, Liu, Qi, Tansey, William P.
Gepubliceerd in Nat Commun (2019)

Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport

door Le, Michelle H., Weissmiller, April M., Monte, Louise, Lin, Po Han, Hexom, Tia C., Natera, Orlangie, Wu, Chengbiao, Rissman, Robert A.
Gepubliceerd in PLoS One (2016)

Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy

door Selfridge, Aaron, Hyun, Nicholas, Chiang, Chai-Chun, Reyna, Sol M., Weissmiller, April M., Shi, Linda Z., Preece, Daryl, Mobley, William C., Berns, Michael W.
Gepubliceerd in Neurophotonics (2015)

Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance

door Thomas, Lance R., Adams, Clare M., Wang, Jing, Weissmiller, April M., Creighton, Joy, Lorey, Shelly L., Liu, Qi, Fesik, Stephen W., Eischen, Christine M., Tansey, William P.
Gepubliceerd in Proc Natl Acad Sci U S A (2019)

Interaction of MYC with Host Cell Factor-1 is meditated by the evolutionarily-conserved Myc box IV motif

door Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Popay, Tessa M., Grieb, Brian C., Qualls, Susan J., Ng, Victoria, Carboneau, Bethany, Lorey, Shelly, Eischen, Christine M., Tansey, William P.
Gepubliceerd in Oncogene (2015)

A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP

door Weissmiller, April M., Natera-Naranjo, Orlangie, Reyna, Sol M., Pearn, Matthew L., Zhao, Xiaobei, Nguyen, Phuong, Cheng, Soan, Goldstein, Lawrence S. B., Tanzi, Rudolph E., Wagner, Steven L., Mobley, William C., Wu, Chengbiao
Gepubliceerd in PLoS One (2015)

Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

door Xu, Wei, Weissmiller, April M., White, Joseph A., Fang, Fang, Wang, Xinyi, Wu, Yiwen, Pearn, Matthew L., Zhao, Xiaobei, Sawa, Mariko, Chen, Shengdi, Gunawardena, Shermali, Ding, Jianqing, Mobley, William C., Wu, Chengbiao
Gepubliceerd in J Clin Invest (2016)

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

door Popay, Tessa M, Wang, Jing, Adams, Clare M, Howard, Gregory Caleb, Codreanu, Simona G, Sherrod, Stacy D, McLean, John A, Thomas, Lance R, Lorey, Shelly L, Machida, Yuichi J, Weissmiller, April M, Eischen, Christine M, Liu, Qi, Tansey, William P
Gepubliceerd in eLife (2021)

Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler

door Woodley, Chase M., Romer, Alexander S., Wang, Jing, Guarnaccia, Alissa D., Elion, David L., Maxwell, Jack N., Guerrazzi, Kiana, McCann, Tyler S., Popay, Tessa M., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Liu, Qi, Tansey, William P., Weissmiller, April M.
Gepubliceerd in Oncogene (2021)

WDR5 is a conserved regulator of protein synthesis gene expression

door Bryan, Audra F, Wang, Jing, Howard, Gregory C, Guarnaccia, Alissa D, Woodley, Chase M, Aho, Erin R, Rellinger, Eric J, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Chung, Dai H, Fesik, Stephen W, Liu, Qi, Weissmiller, April M, Tansey, William P
Gepubliceerd in Nucleic Acids Res (2020)

Impact of WIN site inhibitor on the WDR5 interactome

door Guarnaccia, Alissa D., Rose, Kristie L., Wang, Jing, Zhao, Bin, Popay, Tessa M., Wang, Christina E., Guerrazzi, Kiana, Hill, Salisha, Woodley, Chase M., Hansen, Tyler J., Lorey, Shelly L., Shaw, J. Grace, Payne, William G., Weissmiller, April M., Olejniczak, Edward T., Fesik, Stephen W., Liu, Qi, Tansey, William P.
Gepubliceerd in Cell Rep (2021)

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

door Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.
Gepubliceerd in Cell Rep (2019)