Current advances in using neurotrophic factors to treat neurodegenerative disorders

per Weissmiller, April M, Wu, Chengbiao
Publicat 2012

Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects

per Rodrigues, Elizabeth M., Weissmiller, April M., Goldstein, Lawrence S.B.
Publicat 2012

The MYC–WDR5 Nexus and Cancer

per Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Tansey, William P.
Publicat a Cancer Res (2015)

Targeting WDR5: A WINning Anti-Cancer Strategy?

per Aho, Erin R, Weissmiller, April M, Fesik, Stephen W, Tansey, William P
Publicat a Epigenet Insights (2019)

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons

per Zhao, Xiaobei, Zhou, Yue, Weissmiller, April M., Pearn, Matthew L., Mobley, William C., Wu, Chengbiao
Publicat a J Vis Exp (2014)

Inhibition of MYC by the SMARCB1 tumor suppressor

per Weissmiller, April M., Wang, Jing, Lorey, Shelly L., Howard, Gregory C., Martinez, Ernest, Liu, Qi, Tansey, William P.
Publicat a Nat Commun (2019)

Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport

per Le, Michelle H., Weissmiller, April M., Monte, Louise, Lin, Po Han, Hexom, Tia C., Natera, Orlangie, Wu, Chengbiao, Rissman, Robert A.
Publicat a PLoS One (2016)

Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy

per Selfridge, Aaron, Hyun, Nicholas, Chiang, Chai-Chun, Reyna, Sol M., Weissmiller, April M., Shi, Linda Z., Preece, Daryl, Mobley, William C., Berns, Michael W.
Publicat a Neurophotonics (2015)

Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance

per Thomas, Lance R., Adams, Clare M., Wang, Jing, Weissmiller, April M., Creighton, Joy, Lorey, Shelly L., Liu, Qi, Fesik, Stephen W., Eischen, Christine M., Tansey, William P.
Publicat a Proc Natl Acad Sci U S A (2019)

Interaction of MYC with Host Cell Factor-1 is meditated by the evolutionarily-conserved Myc box IV motif

per Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Popay, Tessa M., Grieb, Brian C., Qualls, Susan J., Ng, Victoria, Carboneau, Bethany, Lorey, Shelly, Eischen, Christine M., Tansey, William P.
Publicat a Oncogene (2015)

A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP

per Weissmiller, April M., Natera-Naranjo, Orlangie, Reyna, Sol M., Pearn, Matthew L., Zhao, Xiaobei, Nguyen, Phuong, Cheng, Soan, Goldstein, Lawrence S. B., Tanzi, Rudolph E., Wagner, Steven L., Mobley, William C., Wu, Chengbiao
Publicat a PLoS One (2015)

Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

per Xu, Wei, Weissmiller, April M., White, Joseph A., Fang, Fang, Wang, Xinyi, Wu, Yiwen, Pearn, Matthew L., Zhao, Xiaobei, Sawa, Mariko, Chen, Shengdi, Gunawardena, Shermali, Ding, Jianqing, Mobley, William C., Wu, Chengbiao
Publicat a J Clin Invest (2016)

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

per Popay, Tessa M, Wang, Jing, Adams, Clare M, Howard, Gregory Caleb, Codreanu, Simona G, Sherrod, Stacy D, McLean, John A, Thomas, Lance R, Lorey, Shelly L, Machida, Yuichi J, Weissmiller, April M, Eischen, Christine M, Liu, Qi, Tansey, William P
Publicat a eLife (2021)

Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler

per Woodley, Chase M., Romer, Alexander S., Wang, Jing, Guarnaccia, Alissa D., Elion, David L., Maxwell, Jack N., Guerrazzi, Kiana, McCann, Tyler S., Popay, Tessa M., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Liu, Qi, Tansey, William P., Weissmiller, April M.
Publicat a Oncogene (2021)

WDR5 is a conserved regulator of protein synthesis gene expression

per Bryan, Audra F, Wang, Jing, Howard, Gregory C, Guarnaccia, Alissa D, Woodley, Chase M, Aho, Erin R, Rellinger, Eric J, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Chung, Dai H, Fesik, Stephen W, Liu, Qi, Weissmiller, April M, Tansey, William P
Publicat a Nucleic Acids Res (2020)

Impact of WIN site inhibitor on the WDR5 interactome

per Guarnaccia, Alissa D., Rose, Kristie L., Wang, Jing, Zhao, Bin, Popay, Tessa M., Wang, Christina E., Guerrazzi, Kiana, Hill, Salisha, Woodley, Chase M., Hansen, Tyler J., Lorey, Shelly L., Shaw, J. Grace, Payne, William G., Weissmiller, April M., Olejniczak, Edward T., Fesik, Stephen W., Liu, Qi, Tansey, William P.
Publicat a Cell Rep (2021)

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

per Aho, Erin R., Wang, Jing, Gogliotti, Rocco D., Howard, Gregory C., Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D., Cheng, Ken, Lorey, Shelly L., Lu, Bin, Wenzel, Sabine, Foshage, Audra M., Alvarado, Joseph, Wang, Feng, Shaw, J. Grace, Zhao, Bin, Weissmiller, April M., Thomas, Lance R., Vakoc, Christopher R., Hall, Matthew D., Hiebert, Scott W., Liu, Qi, Stauffer, Shaun R., Fesik, Stephen W., Tansey, William P.
Publicat a Cell Rep (2019)