STAT5 in hematopoietic stem cell biology and transplantation

par Wang, Zhengqi, Bunting, Kevin D
Publié 2013

STAT5 activation in B-cell acute lymphoblastic leukemia: damned if you do, damned if you don’t

par Wang, Zhengqi, Bunting, Kevin D.
Publié dans Cancer Cell Microenviron (2016)

Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations

par Wang, Zhengqi, Bunting, Kevin D.
Publié dans Oncotarget (2017)

Experimental dataset on electrolyte mixtures containing fluoroethylene carbonate and lithium bis(trifluoromethanesulfonyl)imide

par Wang, Zhengqi, Hofmann, Andreas, Hanemann, Thomas
Publié dans Data Brief (2019)

STAT5 N-domain deleted isoforms are naturally occurring hypomorphs partially rescued in hematopoiesis by transgenic Bcl-2 expression

par Wang, Zhengqi, Li, Geqiang, Bunting, Kevin D
Publié 2014

The Cooperative Relationship between STAT5 and Reactive Oxygen Species in Leukemia: Mechanism and Therapeutic Potential

par Mi, Tian, Wang, Zhengqi, Bunting, Kevin D.
Publié dans Cancers (Basel) (2018)

Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement

par Wang, Zhengqi, Li, Geqiang, Tse, William, Bunting, Kevin D.
Publié 2009

Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis

par Wang, Zhengqi, Medrzycki, Magdalena, Bunting, Silvia T., Bunting, Kevin D.
Publié dans Oncotarget (2015)

Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescence

par Qing, Yulan, Wang, Zhengqi, Bunting, Kevin D., Gerson, Stanton L.
Publié 2014

Mutation of STAT1/3 binding sites in gp130(FXXQ) knock-inmice does not alter hematopoietic stem cell repopulation or self-renewal potential

par Wang, Zhengqi, Kang, Zizhen, Zhang, Yi, Tse, William, Bunting, Kevin D
Publié 2012

Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis

par Lee, Jocelyn A., Wang, Zhengqi, Sambo, Danielle, Bunting, Kevin D., Pallas, David C.
Publié dans J Biol Chem (2018)

Gab2 Promotes Hematopoietic Stem Cell Maintenance and Self-Renewal Synergistically with STAT5

par Li, Geqiang, Wang, Zhengqi, Miskimen, Kristy L., Zhang, Yi, Tse, William, Bunting, Kevin D.
Publié 2010

Dexamethasone-induced Inositol 1,4,5-Trisphosphate Receptor Elevation in Murine Lymphoma Cells Is Not Required for Dexamethasone-mediated Calcium Elevation and Apoptosis

par Davis, Michael C., McColl, Karen S., Zhong, Fei, Wang, Zhengqi, Malone, Michael H., Distelhorst, Clark W.
Publié 2008

IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increa...

par Ohmori, Keitaro, Luo, Yuchun, Jia, Yi, Nishida, Jun, Wang, Zhengqi, Bunting, Kevin D., Wang, Demin, Huang, Hua
Publié 2009

Multiple Apoptotic Defects in Hematopoietic Cells from Mice Lacking Lipocalin 24p3

par Liu, Zhuoming, Yang, Amy, Wang, Zhengqi, Bunting, Kevin D., Davuluri, Gangarao, Green, Michael R., Devireddy, Laxminarayana R.
Publié 2011

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells

par Metts, Jonathan, Bradley, Heath L., Wang, Zhengqi, Shah, Neil P., Kapur, Reuben, Arbiser, Jack L., Bunting, Kevin D.
Publié dans Sci Rep (2017)

Pimozide and Imipramine Blue Exploit Mitochondrial Vulnerabilities and Reactive Oxygen Species to Cooperatively Target High Risk Acute Myeloid Leukemia

par Wang, Zhengqi, Mi, Tian, Bradley, Heath L., Metts, Jonathan, Sabnis, Himalee, Zhu, Wandi, Arbiser, Jack, Bunting, Kevin D.
Publié dans Antioxidants (Basel) (2021)

Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin

par Li, Geqiang, Miskimen, Kristy L., Wang, Zhengqi, Xie, Xiu Yan, Tse, William, Gouilleux, Fabrice, Moriggl, Richard, Bunting, Kevin D.
Publié 2010

STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease

par Li, Geqiang, Miskimen, Kristy L., Wang, Zhengqi, Xie, Xiu Yan, Brenzovich, Jennifer, Ryan, John J., Tse, William, Moriggl, Richard, Bunting, Kevin D.
Publié 2010

STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output

par Li, Geqiang, Wang, Zhengqi, Zhang, Yi, Kang, Zizhen, Haviernikova, Eleonora, Cui, Yongzhi, Hennighausen, Lothar, Moriggl, Richard, Wang, Demin, Tse, William, Bunting, Kevin D.
Publié 2007