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STAT5 N-domain deleted isoforms are naturally occurring hypomorphs partially rescued in hematopoiesis by transgenic Bcl-2 expression

Signal transducer and activator of transcription 5 (STAT5) is a critical regulator of normal and leukemic lympho-myeloid development through activation downstream of early-acting cytokines, their receptors, and JAKs. Truncation of STAT5 can be mediated through alternative translation initiation from...

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Bibliografske podrobnosti
Main Authors: Wang, Zhengqi, Li, Geqiang, Bunting, Kevin D
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165113/
https://ncbi.nlm.nih.gov/pubmed/25232501
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