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Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis

Despite being an attractive molecular target for both lymphoid and myeloid leukemias characterized by activated tyrosine kinases, the molecular and physiological consequences of reduced signal transducer and activator of transcription-5 (Stat5) during leukemogenesis are not well known. Stat5 is a cr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Zhengqi, Medrzycki, Magdalena, Bunting, Silvia T., Bunting, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745704/
https://ncbi.nlm.nih.gov/pubmed/26338970
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