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Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations
Aging is associated with significant changes in hematopoiesis, including clonal dominance, anemia, myeloid malignancies, and reduced activation of signal transducer and activator of transcription 5 (Stat5). In previous studies, Stat5 deletion surprisingly amplified FLT3/ITD(+) myeloid expansion or M...
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| Vydáno v: | Oncotarget |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410237/ https://ncbi.nlm.nih.gov/pubmed/28390194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15236 |
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