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HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency

Cited2 is a transcriptional modulator involved in various biologic processes including fetal liver hematopoiesis. In the present study, the function of Cited2 in adult hematopoiesis was investigated in conditional knockout mice. Deletion of Cited2 using Mx1-Cre resulted in increased hematopoietic st...

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Detalhes bibliográficos
Main Authors: Du, Jinwei, Chen, Yu, Li, Qiang, Han, Xiangzi, Cheng, Cindy, Wang, Zhengqi, Danielpour, David, Dunwoodie, Sally L., Bunting, Kevin D., Yang, Yu-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327457/
https://ncbi.nlm.nih.gov/pubmed/22308296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-387902
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