HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency

Cited2 is a transcriptional modulator involved in various biologic processes including fetal liver hematopoiesis. In the present study, the function of Cited2 in adult hematopoiesis was investigated in conditional knockout mice. Deletion of Cited2 using Mx1-Cre resulted in increased hematopoietic st...

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Bibliografiske detaljer
Main Authors: Du, Jinwei, Chen, Yu, Li, Qiang, Han, Xiangzi, Cheng, Cindy, Wang, Zhengqi, Danielpour, David, Dunwoodie, Sally L., Bunting, Kevin D., Yang, Yu-Chung
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327457/
https://ncbi.nlm.nih.gov/pubmed/22308296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-387902
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