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HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency
Cited2 is a transcriptional modulator involved in various biologic processes including fetal liver hematopoiesis. In the present study, the function of Cited2 in adult hematopoiesis was investigated in conditional knockout mice. Deletion of Cited2 using Mx1-Cre resulted in increased hematopoietic st...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327457/ https://ncbi.nlm.nih.gov/pubmed/22308296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-387902 |
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