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Mutation of STAT1/3 binding sites in gp130(FXXQ) knock-inmice does not alter hematopoietic stem cell repopulation or self-renewal potential

Interleukin (IL)-6 family cytokine signaling through gp130 and signal transducer and activator of transcription (STAT) activation is believed important for early hematopoiesis. To determine whether gp130/STAT1/3 physical interaction is required, we compared hematopoietic repopulating activities of e...

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Autors principals: Wang, Zhengqi, Kang, Zizhen, Zhang, Yi, Tse, William, Bunting, Kevin D
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385990/
https://ncbi.nlm.nih.gov/pubmed/22754757
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