Dexamethasone-induced Inositol 1,4,5-Trisphosphate Receptor Elevation in Murine Lymphoma Cells Is Not Required for Dexamethasone-mediated Calcium Elevation and Apoptosis

Glucocorticosteroid hormones, including dexamethasone, have diverse effects on immature lymphocyte function that ultimately lead to cell death. Previous studies established that glucocorticoid-induced alterations in intracellular calcium homeostasis promote apoptosis, but the mechanism by which gluc...

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Autores principales: Davis, Michael C., McColl, Karen S., Zhong, Fei, Wang, Zhengqi, Malone, Michael H., Distelhorst, Clark W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447640/
https://ncbi.nlm.nih.gov/pubmed/18272518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800269200
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