A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma b...

od Patel, Manish M., Volkov, Oleg A., Leija, Christopher, Lemoff, Andrew, Phillips, Margaret A.
Izdano u PLoS Pathog (2018)

Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozyme

od Xiao, Yanjing, Nguyen, Suong, Kim, Sok Ho, Volkov, Oleg A., Tu, Benjamin P., Phillips, Margaret A.
Izdano 2013

Improved Synthesis of MDL 73811 – a Potent AdoMetDC Inhibitor and Anti-Trypanosomal Compound

od Brockway, Anthony J., Cosner, Casey C., Volkov, Oleg A., Phillips, Margaret A., De Brabander, Jef K.
Izdano u Synthesis (Stuttg) (2016)

Structure of the Cytosolic Part of the Subunit b-Dimer of Escherichia coli F(0)F(1)-ATP Synthase

od Hornung, Tassilo, Volkov, Oleg A., Zaida, Tarek M. A., Delannoy, Sabine, Wise, John G., Vogel, Pia D.
Izdano 2008

Species-Selective Pyrimidineamine Inhibitors of Trypanosoma brucei S-Adenosylmethionine Decarboxylase

od Volkov, Oleg A., Brockway, Anthony J., Wring, Stephen A., Peel, Michael, Chen, Zhe, Phillips, Margaret A., De Brabander, Jef K.
Izdano u J Med Chem (2018)

Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog

od Volkov, Oleg A, Kinch, Lisa, Ariagno, Carson, Deng, Xiaoyi, Zhong, Shihua, Grishin, Nick, Tomchick, Diana R, Chen, Zhe, Phillips, Margaret A
Izdano u eLife (2016)

Synthesis and evaluation of analogs of 5'-(((Z)-4-amino-2-butenyl)methylamino)-5'-deoxyadenosine (MDL 73811, or AbeAdo) – an inhibitor of S-adenosylmethionine decarboxylase with an...

od Brockway, Anthony J., Volkov, Oleg A., Cosner, Casey C., MacMillan, Karen S., Wring, Stephen A., Richardson, Thomas E., Peel, Michael, Phillips, Margaret A., De Brabander, Jef K.
Izdano u Bioorg Med Chem (2017)

Identification of Trypanosoma brucei AdoMetDC inhibitors using a high-throughput mass spectrometry-based assay

od Volkov, Oleg A., Cosner, Casey C., Brockway, Anthony J., Kramer, Martin, Booker, Michael, Zhong, Shihua, Ketcherside, Ariel, Wei, Shuguang, Longgood, Jamie, McCoy, Melissa, Richardson, Thomas E., Wring, Stephen A., Peel, Michael, Klinger, Jeffrey D., Posner, Bruce A., De Brabander, Jef K., Phillips, Margaret A.
Izdano u ACS Infect Dis (2017)