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Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozyme

Human African sleeping sickness (HAT) is caused by the parasitic protozoan Trypanosoma brucei. Polyamine biosynthesis is an important drug target in the treatment of HAT. Previously we showed that trypanosomatid S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme for biosynthesis of the poly...

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Bibliografische gegevens
Hoofdauteurs: Xiao, Yanjing, Nguyen, Suong, Kim, Sok Ho, Volkov, Oleg A., Tu, Benjamin P., Phillips, Margaret A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771639/
https://ncbi.nlm.nih.gov/pubmed/23634831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12226
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