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Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozyme

Human African sleeping sickness (HAT) is caused by the parasitic protozoan Trypanosoma brucei. Polyamine biosynthesis is an important drug target in the treatment of HAT. Previously we showed that trypanosomatid S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme for biosynthesis of the poly...

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Библиографические подробности
Главные авторы: Xiao, Yanjing, Nguyen, Suong, Kim, Sok Ho, Volkov, Oleg A., Tu, Benjamin P., Phillips, Margaret A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771639/
https://ncbi.nlm.nih.gov/pubmed/23634831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12226
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