Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozyme

Human African sleeping sickness (HAT) is caused by the parasitic protozoan Trypanosoma brucei. Polyamine biosynthesis is an important drug target in the treatment of HAT. Previously we showed that trypanosomatid S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme for biosynthesis of the poly...

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Hlavní autoři: Xiao, Yanjing, Nguyen, Suong, Kim, Sok Ho, Volkov, Oleg A., Tu, Benjamin P., Phillips, Margaret A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771639/
https://ncbi.nlm.nih.gov/pubmed/23634831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12226
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