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Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozyme

Human African sleeping sickness (HAT) is caused by the parasitic protozoan Trypanosoma brucei. Polyamine biosynthesis is an important drug target in the treatment of HAT. Previously we showed that trypanosomatid S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme for biosynthesis of the poly...

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Yanjing, Nguyen, Suong, Kim, Sok Ho, Volkov, Oleg A., Tu, Benjamin P., Phillips, Margaret A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771639/
https://ncbi.nlm.nih.gov/pubmed/23634831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12226
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