Vaccine development and trials in low and lower-middle income countries: Key issues, advances and future opportunities

Por Grenham, Amy, Villafana, Tonya
Publicado no Hum Vaccin Immunother (2017)

Generalized ROC methods for immunogenicity data analysis of vaccine phase I studies in a seropositive population

Por Yu, Li, Esser, Mark T., Falloon, Judith, Villafana, Tonya, Yang, Harry
Publicado no Hum Vaccin Immunother (2018)

Hospitalizations for Respiratory Syncytial Virus Among Adults in the United States, 1997–2012

Por Pastula, Susan T., Hackett, Judith, Coalson, Jenna, Jiang, Xiaohui, Villafana, Tonya, Ambrose, Christopher, Fryzek, Jon
Publicado no Open Forum Infect Dis (2017)

Safety, Tolerability, and Pharmacokinetics of MEDI8897, the Respiratory Syncytial Virus Prefusion F-Targeting Monoclonal Antibody with an Extended Half-Life, in Healthy Adults

Por Griffin, M. Pamela, Khan, Anis A., Esser, Mark T., Jensen, Kathryn, Takas, Therese, Kankam, Martin K., Villafana, Tonya, Dubovsky, Filip
Publicado no Antimicrob Agents Chemother (2017)

A Single Dose Monoclonal Antibody (mAb) Immunoprophylaxis Strategy to Prevent RSV Disease in All Infants: Results of the First in Infant Study with MEDI8897

Por Domachowske, Joseph B, Khan, Anis, Esser, Mark T, Jensen, Kathryn M, Takas, Therese, Villafana, Tonya, Dubovsky, Filip, Griffin, M Pamela
Publicado no Open Forum Infect Dis (2017)

Safety, Tolerability and Pharmacokinetics of MEDI8897, an Extended Half-life Single-dose Respiratory Syncytial Virus Prefusion F-targeting Monoclonal Antibody Administered as a Sin...

Por Domachowske, Joseph B., Khan, Anis A., Esser, Mark T., Jensen, Kathryn, Takas, Therese, Villafana, Tonya, Dubovsky, Filip, Griffin, M. Pamela
Publicado no Pediatr Infect Dis J (2018)

An Adjuvanted, Postfusion F Protein–Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults

Por Falloon, Judith, Yu, Jing, Esser, Mark T, Villafana, Tonya, Yu, Li, Dubovsky, Filip, Takas, Therese, Levin, Myron J, Falsey, Ann R
Publicado no J Infect Dis (2017)

Characterization of Circulating RSV Strains Among Patients In The Outsmart RSV Program During the 2015–16 Winter Viral Season in the United States

Por Pastula, Susan, Levin-Sparenberg, Elizabeth, Jiang, Xiaohui, Fryzek, Jon P, Hackett, Judith, Villafana, Tonya, Yu, Li, Esser, Mark T, Tovchigrechko, Andrey, Lu, Bin, Ruzin, Alexey
Publicado no Open Forum Infect Dis (2017)

Recruitment and Retention of Pregnant Women Into Clinical Research Trials: An Overview of Challenges, Facilitators, and Best Practices

Por Frew, Paula M., Saint-Victor, Diane S., Isaacs, Margaret Brewinski, Kim, Sonnie, Swamy, Geeta K., Sheffield, Jeanne S., Edwards, Kathryn M., Villafana, Tonya, Kamagate, Ouda, Ault, Kevin
Publicado no Clin Infect Dis (2014)

Dose Selection for an Adjuvanted Respiratory Syncytial Virus F Protein Vaccine for Older Adults Based on Humoral and Cellular Immune Responses

Por Falloon, Judith, Talbot, H. Keipp, Curtis, Craig, Ervin, John, Krieger, Diane, Dubovsky, Filip, Takas, Therese, Yu, Jing, Yu, Li, Lambert, Stacie L., Villafana, Tonya, Esser, Mark T.
Publicado no Clin Vaccine Immunol (2017)

Characterization of circulating RSV strains among subjects in the OUTSMART-RSV surveillance program during the 2016-17 winter viral season in the United States

Por Ruzin, Alexey, Pastula, Susan T., Levin-Sparenberg, Elizabeth, Jiang, Xiaohui, Fryzek, Jon, Tovchigrechko, Andrey, Lu, Bin, Qi, Yanping, Liu, Hui, Jin, Hong, Yu, Li, Hackett, Judith, Villafana, Tonya, Esser, Mark T.
Publicado no PLoS One (2018)

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01(E) and Protection against P falciparum Clinical Malaria

Por Olotu, Ally, Moris, Philippe, Mwacharo, Jedidah, Vekemans, Johan, Kimani, Domtila, Janssens, Michel, Kai, Oscar, Jongert, Erik, Lievens, Marc, Leach, Amanda, Villafana, Tonya, Savarese, Barbara, Marsh, Kevin, Cohen, Joe, Bejon, Philip
Publicado em 2011

Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine

Por Carter Terrell, Villafana Tonya, Okech Brenda, Ofori-Anyinam Opokua, Greenwood Brian, Kremsner Peter, Drakeley Chris, Oyakhirome Sunny, Bruls Myriam, Vekemans Johan, Swysen Christine, Savarese Barbara, Duse Adriano, Reijman Andrea, Ingram Charlotte, Frean John, Ogutu Bernhards
Publicado em 2011-08-01

Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

Por Horowitz, Amir, Hafalla, Julius C. R., King, Elizabeth, Lusingu, John, Dekker, Denise, Leach, Amanda, Moris, Philippe, Cohen, Joe, Vekemans, Johan, Villafana, Tonya, Corran, Patrick H., Bejon, Philip, Drakeley, Chris J., von Seidlein, Lorenz, Riley, Eleanor M.
Publicado em 2012

A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon

Por Lell, Bertrand, Agnandji, Selidji, von Glasenapp, Isabelle, Haertle, Sonja, Oyakhiromen, Sunny, Issifou, Saadou, Vekemans, Johan, Leach, Amanda, Lievens, Marc, Dubois, Marie-Claude, Demoitie, Marie-Ange, Carter, Terrell, Villafana, Tonya, Ballou, W. Ripley, Cohen, Joe, Kremsner, Peter G.
Publicado em 2009

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02(D) malaria vaccine in infants living in a malaria-endemic region

Por Abdulla, Salim, Salim, Nahya, Machera, Francisca, Kamata, Richard, Juma, Omar, Shomari, Mwanajaa, Kubhoja, Sulende, Mohammed, Ali, Mwangoka, Grace, Aebi, Thomas, Mshinda, Hassan, Schellenberg, David, Carter, Terrell, Villafana, Tonya, Dubois, Marie-Claude, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Cohen, Joe, Ballou, W Ripley, Tanner, Marcel
Publicado em 2013

Effect of the Pre-erythrocytic Candidate Malaria Vaccine RTS,S/AS01(E) on Blood Stage Immunity in Young Children

Por Bejon, Philip, Cook, Jackie, Bergmann-Leitner, Elke, Olotu, Ally, Lusingu, John, Mwacharo, Jedidah, Vekemans, Johan, Njuguna, Patricia, Leach, Amanda, Lievens, Marc, Dutta, Sheetij, von Seidlein, Lorenz, Savarese, Barbara, Villafana, Tonya, Lemnge, Martha M., Cohen, Joe, Marsh, Kevin, Corran, Patrick H., Angov, Evelina, Riley, Eleanor M., Drakeley, Chris J.
Publicado em 2011

Induction of Plasmodium falciparum-Specific CD4(+) T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

Por Agnandji, Selidji T., Fendel, Rolf, Mestré, Michaël, Janssens, Michel, Vekemans, Johan, Held, Jana, Gnansounou, Ferdinand, Haertle, Sonja, von Glasenapp, Isabel, Oyakhirome, Sunny, Mewono, Ludovic, Moris, Philippe, Lievens, Marc, Demoitie, Marie-Ange, Dubois, Patrice M., Villafana, Tonya, Jongert, Erik, Olivier, Aurelie, Cohen, Joe, Esen, Meral, Kremsner, Peter G., Lell, Bertrand, Mordmüller, Benjamin
Publicado em 2011

Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age

Por Bejon, Philip, Lusingu, John, Olotu, Ally, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Mshamu, Salum, Lang, Trudie, Gould, Jayne, Dubois, Marie-Claude, Demoitié, Marie-Ange, Stallaert, Jean-Francois, Vansadia, Preeti, Carter, Terrell, Njuguna, Patricia, Awuondo, Ken O., Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Mturi, Neema, Drakeley, Chris J., Savarese, Barbara, Villafana, Tonya, Ballou, W. Ripley, Cohen, Joe, Riley, Eleanor M., Lemnge, Martha M., Marsh, Kevin, von Seidlein, Lorenz
Publicado em 2008

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a rando...

Por Olotu, Ally, Lusingu, John, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Msham, Salum, Lang, Trudie, Gould, Jayne, Dubois, Marie-Claude, Jongert, Erik, Vansadia, Preeti, Carter, Terrell, Njuguna, Patricia, Awuondo, Ken O, Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Mturi, Neema, Drakeley, Chris J, Savarese, Barbara, Villafana, Tonya, Lapierre, Didier, Ballou, W Ripley, Cohen, Joe, Lemnge, Martha M, Peshu, Norbert, Marsh, Kevin, Riley, Eleanor M, von Seidlein, Lorenz, Bejon, Philip
Publicado em 2011