Dose Selection for an Adjuvanted Respiratory Syncytial Virus F Protein Vaccine for Older Adults Based on Humoral and Cellular Immune Responses

This is the second phase 1 study of a respiratory syncytial virus (RSV) vaccine containing RSV fusion protein (sF) adjuvanted with glucopyranosyl lipid A (GLA) in a squalene-based 2% stable emulsion (GLA-SE). In this randomized, double-blind study, 261 subjects aged ≥60 years received inactivated in...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Falloon, Judith, Talbot, H. Keipp, Curtis, Craig, Ervin, John, Krieger, Diane, Dubovsky, Filip, Takas, Therese, Yu, Jing, Yu, Li, Lambert, Stacie L., Villafana, Tonya, Esser, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585697/
https://ncbi.nlm.nih.gov/pubmed/28679495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00157-17
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