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Generalized ROC methods for immunogenicity data analysis of vaccine phase I studies in a seropositive population
Immunogenicity data from phase 1 vaccine studies can be difficult to interpret, especially in seropositive populations and when multiple assays are used. We developed 3 statistical methods (Youden index [YI] threshold, receiver-operating characteristic relative to baseline [ROC-B], and ROC of postdo...
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| Publicado no: | Hum Vaccin Immunother |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314430/ https://ncbi.nlm.nih.gov/pubmed/29913105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1489191 |
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