A DNA Vaccine for Ebola Virus Is Safe and Immunogenic in a Phase I Clinical Trial

Ebola viruses represent a class of filoviruses that causes severe hemorrhagic fever with high mortality. Recognized first in 1976 in the Democratic Republic of Congo, outbreaks continue to occur in equatorial Africa. A safe and effective Ebola virus vaccine is needed because of its continued emergen...

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Main Authors: Martin, Julie E., Sullivan, Nancy J., Enama, Mary E., Gordon, Ingelise J., Roederer, Mario, Koup, Richard A., Bailer, Robert T., Chakrabarti, Bimal K., Bailey, Michael A., Gomez, Phillip L., Andrews, Charla A., Moodie, Zoe, Gu, Lin, Stein, Judith A., Nabel, Gary J., Graham, Barney S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Vaccine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1656552/
https://ncbi.nlm.nih.gov/pubmed/16988008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00162-06
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