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Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV-1 DNA Candidate Vaccine

BACKGROUND: Gene-based vaccine delivery is an important strategy in the development of a preventive vaccine for acquired immunodeficiency syndrome (AIDS). Vaccine Research Center (VRC) 004 is the first phase 1 dose-escalation study of a multiclade HIV-1 DNA vaccine. METHODS: VRC-HIVDNA009-00-VP is a...

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書誌詳細
主要な著者: Graham, Barney S., Koup, Richard A., Roederer, Mario, Bailer, Robert T., Enama, Mary E., Moodie, Zoe, Martin, Julie E., McCluskey, Margaret M., Chakrabarti, Bimal K., Lamoreaux, Laurie, Andrews, Charla A., Gomez, Phillip L., Mascola, John R., Nabel, Gary J.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428069/
https://ncbi.nlm.nih.gov/pubmed/17109336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/509259
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