Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV-1 DNA Candidate Vaccine

BACKGROUND: Gene-based vaccine delivery is an important strategy in the development of a preventive vaccine for acquired immunodeficiency syndrome (AIDS). Vaccine Research Center (VRC) 004 is the first phase 1 dose-escalation study of a multiclade HIV-1 DNA vaccine. METHODS: VRC-HIVDNA009-00-VP is a...

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Hoofdauteurs: Graham, Barney S., Koup, Richard A., Roederer, Mario, Bailer, Robert T., Enama, Mary E., Moodie, Zoe, Martin, Julie E., McCluskey, Margaret M., Chakrabarti, Bimal K., Lamoreaux, Laurie, Andrews, Charla A., Gomez, Phillip L., Mascola, John R., Nabel, Gary J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428069/
https://ncbi.nlm.nih.gov/pubmed/17109336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/509259
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