Safety, Immunogenicity and Efficacy of Modified Vaccinia Ankara (MVA) Against Dryvax(®) Challenge in Vaccinia-Naïve and Vaccinia-Immune Individuals

Modified vaccinia Ankara (MVA) was evaluated as an alternative to Dryvax(®) in vaccinia-naïve and immune adult volunteers. Subjects received intramuscular MVA or placebo followed by Dryvax(®) challenge at 3 months. Two or more doses of MVA prior to Dryvax(®) reduced severity of lesion formation, dec...

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Hlavní autoři: Parrino, Janie, McCurdy, Lewis H., Larkin, Brenda D., Gordon, Ingelise J., Rucker, Steven E., Enama, Mary E., Koup, Richard A., Roederer, Mario, Bailer, Robert T., Moodie, Zoe, Gu, Lin, Yan, Lihan, Graham, Barney S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892755/
https://ncbi.nlm.nih.gov/pubmed/17126963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.10.04
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