Safety, Immunogenicity and Efficacy of Modified Vaccinia Ankara (MVA) Against Dryvax(®) Challenge in Vaccinia-Naïve and Vaccinia-Immune Individuals

Modified vaccinia Ankara (MVA) was evaluated as an alternative to Dryvax(®) in vaccinia-naïve and immune adult volunteers. Subjects received intramuscular MVA or placebo followed by Dryvax(®) challenge at 3 months. Two or more doses of MVA prior to Dryvax(®) reduced severity of lesion formation, dec...

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Main Authors:	Parrino, Janie, McCurdy, Lewis H., Larkin, Brenda D., Gordon, Ingelise J., Rucker, Steven E., Enama, Mary E., Koup, Richard A., Roederer, Mario, Bailer, Robert T., Moodie, Zoe, Gu, Lin, Yan, Lihan, Graham, Barney S.
Format:	Artigo
Language:	Inglês
Published:	2006
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1892755/ https://ncbi.nlm.nih.gov/pubmed/17126963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.10.04
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Safety, Immunogenicity and Efficacy of Modified Vaccinia Ankara (MVA) Against Dryvax(®) Challenge in Vaccinia-Naïve and Vaccinia-Immune Individuals

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