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Safety, Immunogenicity and Efficacy of Modified Vaccinia Ankara (MVA) Against Dryvax(®) Challenge in Vaccinia-Naïve and Vaccinia-Immune Individuals
Modified vaccinia Ankara (MVA) was evaluated as an alternative to Dryvax(®) in vaccinia-naïve and immune adult volunteers. Subjects received intramuscular MVA or placebo followed by Dryvax(®) challenge at 3 months. Two or more doses of MVA prior to Dryvax(®) reduced severity of lesion formation, dec...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892755/ https://ncbi.nlm.nih.gov/pubmed/17126963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.10.04 |
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