Induction of Plasmodium falciparum-Specific CD4(+) T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

The recombinant circumsporozoite protein (CS) based vaccine, RTS,S, confers protection against Plasmodium falciparum infection in controlled challenge trials and in field studies. The RTS,S recombinant antigen has been formulated with two adjuvant systems, AS01 and AS02, which have both been shown t...

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Hauptverfasser: Agnandji, Selidji T., Fendel, Rolf, Mestré, Michaël, Janssens, Michel, Vekemans, Johan, Held, Jana, Gnansounou, Ferdinand, Haertle, Sonja, von Glasenapp, Isabel, Oyakhirome, Sunny, Mewono, Ludovic, Moris, Philippe, Lievens, Marc, Demoitie, Marie-Ange, Dubois, Patrice M., Villafana, Tonya, Jongert, Erik, Olivier, Aurelie, Cohen, Joe, Esen, Meral, Kremsner, Peter G., Lell, Bertrand, Mordmüller, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073948/
https://ncbi.nlm.nih.gov/pubmed/21494604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018559
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