Induction of Plasmodium falciparum-Specific CD4(+) T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

The recombinant circumsporozoite protein (CS) based vaccine, RTS,S, confers protection against Plasmodium falciparum infection in controlled challenge trials and in field studies. The RTS,S recombinant antigen has been formulated with two adjuvant systems, AS01 and AS02, which have both been shown t...

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Main Authors: Agnandji, Selidji T., Fendel, Rolf, Mestré, Michaël, Janssens, Michel, Vekemans, Johan, Held, Jana, Gnansounou, Ferdinand, Haertle, Sonja, von Glasenapp, Isabel, Oyakhirome, Sunny, Mewono, Ludovic, Moris, Philippe, Lievens, Marc, Demoitie, Marie-Ange, Dubois, Patrice M., Villafana, Tonya, Jongert, Erik, Olivier, Aurelie, Cohen, Joe, Esen, Meral, Kremsner, Peter G., Lell, Bertrand, Mordmüller, Benjamin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073948/
https://ncbi.nlm.nih.gov/pubmed/21494604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018559
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