A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon

BACKGROUND: The malaria vaccine candidate antigen RTS,S includes parts of the pre-erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two Adjuvant Systems are in development for this vaccine, an oil-in water emulsion – based formulation (AS02) and a formulation base...

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Détails bibliographiques
Auteurs principaux: Lell, Bertrand, Agnandji, Selidji, von Glasenapp, Isabelle, Haertle, Sonja, Oyakhiromen, Sunny, Issifou, Saadou, Vekemans, Johan, Leach, Amanda, Lievens, Marc, Dubois, Marie-Claude, Demoitie, Marie-Ange, Carter, Terrell, Villafana, Tonya, Ballou, W. Ripley, Cohen, Joe, Kremsner, Peter G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763199/
https://ncbi.nlm.nih.gov/pubmed/19859560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007611
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