Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age

BACKGROUND: Plasmodium falciparum malaria is a pressing global health problem. A previous study of the malaria vaccine RTS,S (which targets the circumsporozoite protein), given with an adjuvant system (AS02A), showed a 30% rate of protection against clinical malaria in children 1 to 4 years of age....

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Main Authors: Bejon, Philip, Lusingu, John, Olotu, Ally, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Mshamu, Salum, Lang, Trudie, Gould, Jayne, Dubois, Marie-Claude, Demoitié, Marie-Ange, Stallaert, Jean-Francois, Vansadia, Preeti, Carter, Terrell, Njuguna, Patricia, Awuondo, Ken O., Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Mturi, Neema, Drakeley, Chris J., Savarese, Barbara, Villafana, Tonya, Ballou, W. Ripley, Cohen, Joe, Riley, Eleanor M., Lemnge, Martha M., Marsh, Kevin, von Seidlein, Lorenz
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655100/
https://ncbi.nlm.nih.gov/pubmed/19064627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0807381
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