Structural Basis for Increased Toxicity of Pathological Aβ(42):Aβ(40) Ratios in Alzheimer Disease

Por Pauwels, Kris, Williams, Thomas L., Morris, Kyle L., Jonckheere, Wim, Vandersteen, Annelies, Kelly, Geoff, Schymkowitz, Joost, Rousseau, Frederic, Pastore, Annalisa, Serpell, Louise C., Broersen, Kerensa
Publicado em 2012

Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool

Por Vandersteen, Annelies, Masman, Marcelo F., De Baets, Greet, Jonckheere, Wim, van der Werf, Kees, Marrink, Siewert J., Rozenski, Jef, Benilova, Iryna, De Strooper, Bart, Subramaniam, Vinod, Schymkowitz, Joost, Rousseau, Frederic, Broersen, Kerensa
Publicado em 2012

Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β′-site increases Aβ generation†

Por Zhou, Lujia, Brouwers, Nathalie, Benilova, Iryna, Vandersteen, Annelies, Mercken, Marc, Van Laere, Koen, Van Damme, Philip, Demedts, David, Van Leuven, Fred, Sleegers, Kristel, Broersen, Kerensa, Van Broeckhoven, Christine, Vandenberghe, Rik, De Strooper, Bart
Publicado em 2011

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

Por Chávez-Gutiérrez, Lucía, Bammens, Leen, Benilova, Iryna, Vandersteen, Annelies, Benurwar, Manasi, Borgers, Marianne, Lismont, Sam, Zhou, Lujia, Van Cleynenbreugel, Simon, Esselmann, Hermann, Wiltfang, Jens, Serneels, Lutgarde, Karran, Eric, Gijsen, Harrie, Schymkowitz, Joost, Rousseau, Frederic, Broersen, Kerensa, De Strooper, Bart
Publicado em 2012

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ(42) to Aβ(40) ratio

Por Kuperstein, Inna, Broersen, Kerensa, Benilova, Iryna, Rozenski, Jef, Jonckheere, Wim, Debulpaep, Maja, Vandersteen, Annelies, Segers-Nolten, Ine, Van Der Werf, Kees, Subramaniam, Vinod, Braeken, Dries, Callewaert, Geert, Bartic, Carmen, D'Hooge, Rudi, Martins, Ivo Cristiano, Rousseau, Frederic, Schymkowitz, Joost, De Strooper, Bart
Publicado em 2010