Increased Aggregation Is More Frequently Associated to Human Disease-Associated Mutations Than to Neutral Polymorphisms

di De Baets, Greet, Van Doorn, Loic, Rousseau, Frederic, Schymkowitz, Joost
Pubblicato in PLoS Comput Biol (2015)

AmyPro: a database of proteins with validated amyloidogenic regions

di Varadi, Mihaly, De Baets, Greet, Vranken, Wim F, Tompa, Peter, Pancsa, Rita
Pubblicato in Nucleic Acids Res (2018)

An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins

di De Baets, Greet, Reumers, Joke, Delgado Blanco, Javier, Dopazo, Joaquin, Schymkowitz, Joost, Rousseau, Frederic
Pubblicazione 2011

High‐throughput discovery of functional disordered regions: investigation of transactivation domains

di Ravarani, Charles NJ, Erkina, Tamara Y, De Baets, Greet, Dudman, Daniel C, Erkine, Alexandre M, Babu, M Madan
Pubblicato in Mol Syst Biol (2018)

SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

di De Baets, Greet, Van Durme, Joost, Reumers, Joke, Maurer-Stroh, Sebastian, Vanhee, Peter, Dopazo, Joaquin, Schymkowitz, Joost, Rousseau, Frederic
Pubblicazione 2012

α-Galactosidase Aggregation Is a Determinant of Pharmacological Chaperone Efficacy on Fabry Disease Mutants

di Siekierska, Aleksandra, De Baets, Greet, Reumers, Joke, Gallardo, Rodrigo, Rudyak, Stanislav, Broersen, Kerensa, Couceiro, Jose, Van Durme, Joost, Schymkowitz, Joost, Rousseau, Frederic
Pubblicazione 2012

Sequence-dependent Internalization of Aggregating Peptides

di Couceiro, José R., Gallardo, Rodrigo, De Smet, Frederik, De Baets, Greet, Baatsen, Pieter, Annaert, Wim, Roose, Kenny, Saelens, Xavier, Schymkowitz, Joost, Rousseau, Frederic
Pubblicato in J Biol Chem (2015)

Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool

di Vandersteen, Annelies, Masman, Marcelo F., De Baets, Greet, Jonckheere, Wim, van der Werf, Kees, Marrink, Siewert J., Rozenski, Jef, Benilova, Iryna, De Strooper, Bart, Subramaniam, Vinod, Schymkowitz, Joost, Rousseau, Frederic, Broersen, Kerensa
Pubblicazione 2012

Structural hot spots for the solubility of globular proteins

di Ganesan, Ashok, Siekierska, Aleksandra, Beerten, Jacinte, Brams, Marijke, Van Durme, Joost, De Baets, Greet, Van der Kant, Rob, Gallardo, Rodrigo, Ramakers, Meine, Langenberg, Tobias, Wilkinson, Hannah, De Smet, Frederik, Ulens, Chris, Rousseau, Frederic, Schymkowitz, Joost
Pubblicato in Nat Commun (2016)

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

di Boeynaems, Steven, Bogaert, Elke, Michiels, Emiel, Gijselinck, Ilse, Sieben, Anne, Jovičić, Ana, De Baets, Greet, Scheveneels, Wendy, Steyaert, Jolien, Cuijt, Ivy, Verstrepen, Kevin J., Callaerts, Patrick, Rousseau, Frederic, Schymkowitz, Joost, Cruts, Marc, Van Broeckhoven, Christine, Van Damme, Philip, Gitler, Aaron D., Robberecht, Wim, Van Den Bosch, Ludo
Pubblicato in Sci Rep (2016)

Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

di Gijselinck, Ilse, Van Mossevelde, Sara, van der Zee, Julie, Sieben, Anne, Philtjens, Stéphanie, Heeman, Bavo, Engelborghs, Sebastiaan, Vandenbulcke, Mathieu, De Baets, Greet, Bäumer, Veerle, Cuijt, Ivy, Van den Broeck, Marleen, Peeters, Karin, Mattheijssens, Maria, Rousseau, Frederic, Vandenberghe, Rik, De Jonghe, Peter, Cras, Patrick, De Deyn, Peter P., Martin, Jean-Jacques, Cruts, Marc, Van Broeckhoven, Christine
Pubblicato in Neurology (2015)

Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability

di Cacace, Rita, Heeman, Bavo, Van Mossevelde, Sara, De Roeck, Arne, Hoogmartens, Julie, De Rijk, Peter, Gossye, Helena, De Vos, Kristof, De Coster, Wouter, Strazisar, Mojca, De Baets, Greet, Schymkowitz, Joost, Rousseau, Frederic, Geerts, Nathalie, De Pooter, Tim, Peeters, Karin, Sieben, Anne, Martin, Jean-Jacques, Engelborghs, Sebastiaan, Salmon, Eric, Santens, Patrick, Vandenberghe, Rik, Cras, Patrick, P. De Deyn, Peter, C. van Swieten, John, M. van Duijn, Cornelia, van der Zee, Julie, Sleegers, Kristel, Van Broeckhoven, Christine
Pubblicato in Acta Neuropathol (2019)