Increased Aggregation Is More Frequently Associated to Human Disease-Associated Mutations Than to Neutral Polymorphisms

Por De Baets, Greet, Van Doorn, Loic, Rousseau, Frederic, Schymkowitz, Joost
Publicado no PLoS Comput Biol (2015)

AmyPro: a database of proteins with validated amyloidogenic regions

Por Varadi, Mihaly, De Baets, Greet, Vranken, Wim F, Tompa, Peter, Pancsa, Rita
Publicado no Nucleic Acids Res (2018)

An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins

Por De Baets, Greet, Reumers, Joke, Delgado Blanco, Javier, Dopazo, Joaquin, Schymkowitz, Joost, Rousseau, Frederic
Publicado em 2011

High‐throughput discovery of functional disordered regions: investigation of transactivation domains

Por Ravarani, Charles NJ, Erkina, Tamara Y, De Baets, Greet, Dudman, Daniel C, Erkine, Alexandre M, Babu, M Madan
Publicado no Mol Syst Biol (2018)

SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

Por De Baets, Greet, Van Durme, Joost, Reumers, Joke, Maurer-Stroh, Sebastian, Vanhee, Peter, Dopazo, Joaquin, Schymkowitz, Joost, Rousseau, Frederic
Publicado em 2012

α-Galactosidase Aggregation Is a Determinant of Pharmacological Chaperone Efficacy on Fabry Disease Mutants

Por Siekierska, Aleksandra, De Baets, Greet, Reumers, Joke, Gallardo, Rodrigo, Rudyak, Stanislav, Broersen, Kerensa, Couceiro, Jose, Van Durme, Joost, Schymkowitz, Joost, Rousseau, Frederic
Publicado em 2012

Sequence-dependent Internalization of Aggregating Peptides

Por Couceiro, José R., Gallardo, Rodrigo, De Smet, Frederik, De Baets, Greet, Baatsen, Pieter, Annaert, Wim, Roose, Kenny, Saelens, Xavier, Schymkowitz, Joost, Rousseau, Frederic
Publicado no J Biol Chem (2015)

Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool

Por Vandersteen, Annelies, Masman, Marcelo F., De Baets, Greet, Jonckheere, Wim, van der Werf, Kees, Marrink, Siewert J., Rozenski, Jef, Benilova, Iryna, De Strooper, Bart, Subramaniam, Vinod, Schymkowitz, Joost, Rousseau, Frederic, Broersen, Kerensa
Publicado em 2012

Structural hot spots for the solubility of globular proteins

Por Ganesan, Ashok, Siekierska, Aleksandra, Beerten, Jacinte, Brams, Marijke, Van Durme, Joost, De Baets, Greet, Van der Kant, Rob, Gallardo, Rodrigo, Ramakers, Meine, Langenberg, Tobias, Wilkinson, Hannah, De Smet, Frederik, Ulens, Chris, Rousseau, Frederic, Schymkowitz, Joost
Publicado no Nat Commun (2016)

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD

Por Boeynaems, Steven, Bogaert, Elke, Michiels, Emiel, Gijselinck, Ilse, Sieben, Anne, Jovičić, Ana, De Baets, Greet, Scheveneels, Wendy, Steyaert, Jolien, Cuijt, Ivy, Verstrepen, Kevin J., Callaerts, Patrick, Rousseau, Frederic, Schymkowitz, Joost, Cruts, Marc, Van Broeckhoven, Christine, Van Damme, Philip, Gitler, Aaron D., Robberecht, Wim, Van Den Bosch, Ludo
Publicado no Sci Rep (2016)

Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

Por Gijselinck, Ilse, Van Mossevelde, Sara, van der Zee, Julie, Sieben, Anne, Philtjens, Stéphanie, Heeman, Bavo, Engelborghs, Sebastiaan, Vandenbulcke, Mathieu, De Baets, Greet, Bäumer, Veerle, Cuijt, Ivy, Van den Broeck, Marleen, Peeters, Karin, Mattheijssens, Maria, Rousseau, Frederic, Vandenberghe, Rik, De Jonghe, Peter, Cras, Patrick, De Deyn, Peter P., Martin, Jean-Jacques, Cruts, Marc, Van Broeckhoven, Christine
Publicado no Neurology (2015)

Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability

Por Cacace, Rita, Heeman, Bavo, Van Mossevelde, Sara, De Roeck, Arne, Hoogmartens, Julie, De Rijk, Peter, Gossye, Helena, De Vos, Kristof, De Coster, Wouter, Strazisar, Mojca, De Baets, Greet, Schymkowitz, Joost, Rousseau, Frederic, Geerts, Nathalie, De Pooter, Tim, Peeters, Karin, Sieben, Anne, Martin, Jean-Jacques, Engelborghs, Sebastiaan, Salmon, Eric, Santens, Patrick, Vandenberghe, Rik, Cras, Patrick, P. De Deyn, Peter, C. van Swieten, John, M. van Duijn, Cornelia, van der Zee, Julie, Sleegers, Kristel, Van Broeckhoven, Christine
Publicado no Acta Neuropathol (2019)