Sequence-dependent Internalization of Aggregating Peptides

Recently, a number of aggregation disease polypeptides have been shown to spread from cell to cell, thereby displaying prionoid behavior. Studying aggregate internalization, however, is often hampered by the complex kinetics of the aggregation process, resulting in the concomitant uptake of aggregat...

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發表在:J Biol Chem
Main Authors: Couceiro, José R., Gallardo, Rodrigo, De Smet, Frederik, De Baets, Greet, Baatsen, Pieter, Annaert, Wim, Roose, Kenny, Saelens, Xavier, Schymkowitz, Joost, Rousseau, Frederic
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281728/
https://ncbi.nlm.nih.gov/pubmed/25391649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586636
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