Sequence-dependent Internalization of Aggregating Peptides

Recently, a number of aggregation disease polypeptides have been shown to spread from cell to cell, thereby displaying prionoid behavior. Studying aggregate internalization, however, is often hampered by the complex kinetics of the aggregation process, resulting in the concomitant uptake of aggregat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Couceiro, José R., Gallardo, Rodrigo, De Smet, Frederik, De Baets, Greet, Baatsen, Pieter, Annaert, Wim, Roose, Kenny, Saelens, Xavier, Schymkowitz, Joost, Rousseau, Frederic
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281728/
https://ncbi.nlm.nih.gov/pubmed/25391649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586636
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