Linkage of CD8(+) T cell exhaustion with high-fat diet-induced tumourigenesis

Por Kado, Tomonobu, Nawaz, Allah, Takikawa, Akiko, Usui, Isao, Tobe, Kazuyuki
Publicado no Sci Rep (2019)

No Negative Impact of a National State of Emergency by COVID-19 Outbreak on Hemoglobin A1c Levels in Patients With Type 2 Diabetes Living in Semi-Rural Japan

Por Aso, Yoshimasa, Iijima, Toshie, Tomaru, Takuya, Jojima, Teruo, Usui, Isao
Publicado no Am J Med Sci (2021)

Insulin-Induced GLUT4 Translocation Involves Protein Kinase C-λ-Mediated Functional Coupling between Rab4 and the Motor Protein Kinesin

Por Imamura, Takeshi, Huang, Jie, Usui, Isao, Satoh, Hiroaki, Bever, Jennie, Olefsky, Jerrold M.
Publicado em 2003

Mammalian Target of Rapamycin Pathway Regulates Insulin Signaling via Subcellular Redistribution of Insulin Receptor Substrate 1 and Integrates Nutritional Signals and Metabolic Si...

Por Takano, Atsuko, Usui, Isao, Haruta, Tetsuro, Kawahara, Junko, Uno, Tatsuhito, Iwata, Minoru, Kobayashi, Masashi
Publicado em 2001

M2 macrophages in metabolism

Por Fujisaka, Shiho, Usui, Isao, Nawaz, Allah, Takikawa, Akiko, Kado, Tomonobu, Igarashi, Yoshiko, Tobe, Kazuyuki
Publicado no Diabetol Int (2016)

NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing α-Ketoglutarate-Mediated Histone H3K9 Demethylation at the PPARγ Promoter

Por Okabe, Keisuke, Nawaz, Allah, Nishida, Yasuhiro, Yaku, Keisuke, Usui, Isao, Tobe, Kazuyuki, Nakagawa, Takashi
Publicado no Front Cell Dev Biol (2020)

Adenovirus-mediated chronic “hyper-resistinemia” leads to in vivo insulin resistance in normal rats

Por Satoh, Hiroaki, Nguyen, M.T. Audrey, Miles, Philip D.G., Imamura, Takeshi, Usui, Isao, Olefsky, Jerrold M.
Publicado em 2004

GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation

Por Usui, Isao, Imamura, Takeshi, Satoh, Hiroaki, Huang, Jie, Babendure, Jennie L, Hupfeld, Christopher J, Olefsky, Jerrold M
Publicado em 2004

Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway

Por Kobashi, Chikaaki, Asamizu, Sachie, Ishiki, Manabu, Iwata, Minoru, Usui, Isao, Yamazaki, Katusuya, Tobe, Kazuyuki, Kobayashi, Masashi, Urakaze, Masaharu
Publicado em 2009

Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report

Por Kunii, Tomohisa, Iijima, Toshie, Jojima, Teruo, Shimizu, Masanori, Kase, Masato, Sakurai, Shintaro, Kogai, Takahiko, Usui, Isao, Aso, Yoshimasa
Publicado no J Med Case Rep (2019)

Bullous pemphigoid associated with dipeptidyl peptidase‐4 inhibitor showing unfavorable outcomes despite immediate discontinuation of medication

Por Shinohara, Yasutake, Iijima, Toshie, Sakurai, Shintaro, Jojima, Teruo, Ohira, Eriko, Hayashi, Shujiro, Usui, Isao, Igawa, Ken, Aso, Yoshimasa
Publicado no Clin Case Rep (2020)

β-Arrestin-1 Competitively Inhibits Insulin-Induced Ubiquitination and Degradation of Insulin Receptor Substrate 1

Por Usui, Isao, Imamura, Takeshi, Huang, Jie, Satoh, Hiroaki, Shenoy, Sudha K., Lefkowitz, Robert J., Hupfeld, Christopher J., Olefsky, Jerrold M.
Publicado em 2004

Involvement of Both G(q/11) and G(s) Proteins in Gonadotropin-releasing Hormone Receptor-mediated Signaling in LβT2 Cells

Por Liu, Fujun, Usui, Isao, Evans, Lui Guojing, Austin, Darrell A., Mellon, Pamela L., Olefsky, Jerrold M., Webster, Nicholas J. G.
Publicado em 2002

SIRT1-mediated eNAMPT secretion from adipose tissue regulates hypothalamic NAD(+) and function in mice

Por Yoon, Myeong Jin, Yoshida, Mitsukuni, Johnson, Sean, Takikawa, Akiko, Usui, Isao, Tobe, Kazuyuki, Nakagawa, Takashi, Yoshino, Jun, Imai, Shin-ichiro
Publicado no Cell Metab (2015)

The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expres...

Por Jojima, Teruo, Wakamatsu, Sho, Kase, Masato, Iijima, Toshie, Maejima, Yuko, Shimomura, Kenju, Kogai, Takahiko, Tomaru, Takuya, Usui, Isao, Aso, Yoshimasa
Publicado no Int J Mol Sci (2019)

Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age‐associated insulin resistance

Por Gulshan, Maryam, Yaku, Keisuke, Okabe, Keisuke, Mahmood, Arshad, Sasaki, Tsutomu, Yamamoto, Masashi, Hikosaka, Keisuke, Usui, Isao, Kitamura, Tadahiro, Tobe, Kazuyuki, Nakagawa, Takashi
Publicado no Aging Cell (2018)

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

Por Fujisaka, Shiho, Usui, Isao, Bukhari, Agussalim, Ikutani, Masashi, Oya, Takeshi, Kanatani, Yukiko, Tsuneyama, Koichi, Nagai, Yoshinori, Takatsu, Kiyoshi, Urakaze, Masaharu, Kobayashi, Masashi, Tobe, Kazuyuki
Publicado em 2009

Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice

Por Takikawa, Akiko, Usui, Isao, Fujisaka, Shiho, Tsuneyama, Koichi, Okabe, Keisuke, Nakagawa, Takashi, Nawaz, Allah, Kado, Tomonobu, Jojima, Teruo, Aso, Yoshimasa, Hayakawa, Yoshihiro, Yagi, Kunikimi, Tobe, Kazuyuki
Publicado no J Diabetes Investig (2019)

Effects of luseogliflozin on arterial properties in patients with type 2 diabetes mellitus: The multicenter, exploratory LUSCAR study

Por Kario, Kazuomi, Okada, Kenta, Murata, Mitsunobu, Suzuki, Daisuke, Yamagiwa, Kayo, Abe, Yasuhisa, Usui, Isao, Tsuchiya, Norihiro, Iwashita, Chie, Harada, Noriko, Okawara, Yukie, Ishibashi, Shun, Hoshide, Satoshi
Publicado no J Clin Hypertens (Greenwich) (2020)

CD‐1(db/db) mice: A novel type 2 diabetic mouse model with progressive kidney fibrosis

Por Mizunuma, Yuiko, Kanasaki, Keizo, Nitta, Kyoko, Nakamura, Yuka, Ishigaki, Yasuhito, Takagaki, Yuta, Kitada, Munehiro, Li, Shaolan, Liu, Haijie, Li, Jinpeng, Usui, Isao, Aso, Yoshimasa, Koya, Daisuke
Publicado no J Diabetes Investig (2020)