Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age‐associated insulin resistance

Nicotinamide adenine dinucleotide (NAD) is an important cofactor that regulates various biological processes, including metabolism and gene expression. As a coenzyme, NAD controls mitochondrial respiration through enzymes of the tricarboxylic acid (TCA) cycle, β‐oxidation, and oxidative phosphorylat...

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Veröffentlicht in:Aging Cell
Hauptverfasser: Gulshan, Maryam, Yaku, Keisuke, Okabe, Keisuke, Mahmood, Arshad, Sasaki, Tsutomu, Yamamoto, Masashi, Hikosaka, Keisuke, Usui, Isao, Kitamura, Tadahiro, Tobe, Kazuyuki, Nakagawa, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052485/
https://ncbi.nlm.nih.gov/pubmed/29901258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12798
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