Reconstruction of a pathway of antigen processing and class II MHC peptide capture

nork Moss, Catherine X, Tree, Timothy I, Watts, Colin
Argitaratua 2007

Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?

nork Hull, Caroline M., Peakman, Mark, Tree, Timothy I. M.
Argitaratua izan da Diabetologia (2017)

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides

nork Ellis, Richard J, Varela-Calvino, Ruben, Tree, Timothy I M, Peakman, Mark
Argitaratua 2005

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

nork Tree, Timothy I.M., Lawson, Jennifer, Edwards, Hannah, Skowera, Ania, Arif, Sefina, Roep, Bart O., Peakman, Mark
Argitaratua 2010

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

nork Arif, Sefina, Tree, Timothy I., Astill, Thomas P., Tremble, Jennifer M., Bishop, Amanda J., Dayan, Colin M., Roep, Bart O., Peakman, Mark
Argitaratua 2004

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

nork Ahmed, Simi, Cerosaletti, Karen, James, Eddie, Long, S. Alice, Mannering, Stuart, Speake, Cate, Nakayama, Maki, Tree, Timothy, Roep, Bart O., Herold, Kevan C., Brusko, Todd M.
Argitaratua izan da Diabetes (2019)

Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner

nork Carty, Fiona, Corbett, Jennifer M., Cunha, João Paulo M. C. M., Reading, James L., Tree, Timothy I. M., Ting, Anthony E., Stubblefield, Samantha R., English, Karen
Argitaratua izan da Front Immunol (2018)

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects

nork Arif, Sefina, Pujol-Autonell, Irma, Kamra, Yogesh, Williams, Evangelia, Yusuf, Norkhairin, Domingo-Vila, Clara, Shahrabi, Yasaman, Pollock, Emily, Khatri, Leena, Peakman, Mark, Tree, Timothy, Lorenc, Anna
Argitaratua izan da Front Immunol (2021)

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

nork Allen, Jennifer S., Pang, Karl, Skowera, Ania, Ellis, Richard, Rackham, Chloe, Lozanoska-Ochser, Biliana, Tree, Timothy, Leslie, R. David G., Tremble, Jennifer M., Dayan, Colin M., Peakman, Mark
Argitaratua 2009

GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells

nork Arif, Sefina, Gomez-Tourino, Iria, Kamra, Yogesh, Pujol-Autonell, Irma, Hanton, Emily, Tree, Timothy, Melandri, Daisy, Hull, Caroline, Wherrett, Diane K., Beam, Craig, Roep, Bart O., Lorenc, Anna, Peakman, Mark
Argitaratua izan da Diabetologia (2020)

Type 1 Diabetes-associated IL2RAvariationlowers IL-2 signaling and contributes to diminished CD4(+)CD25(+) regulatory T-cell function

nork Garg, Garima, Tyler, Jennifer R, Yang, Jennie H M, Cutler, Antony J, Downes, Kate, Pekalski, Marcin, Bell, Louise, Nutland, Sarah, Peakman, Mark, Todd, John A, Wicker, Linda S, Tree, Timothy I M
Argitaratua 2012

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis

nork Lu, Ching-Hua, Allen, Kezia, Oei, Felicia, Leoni, Emanuela, Kuhle, Jens, Tree, Timothy, Fratta, Pietro, Sharma, Nikhil, Sidle, Katie, Howard, Robin, Orrell, Richard, Fish, Mark, Greensmith, Linda, Pearce, Neil, Gallo, Valentina, Malaspina, Andrea
Argitaratua izan da Neurol Neuroimmunol Neuroinflamm (2016)

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

nork Arif, Sefina, Moore, Fabrice, Marks, Katherine, Bouckenooghe, Thomas, Dayan, Colin M., Planas, Raquel, Vives-Pi, Marta, Powrie, Jake, Tree, Timothy, Marchetti, Piero, Huang, Guo Cai, Gurzov, Esteban N., Pujol-Borrell, Ricardo, Eizirik, Decio L., Peakman, Mark
Argitaratua 2011

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors

nork Whitehouse, Gavin, Gray, Elizabeth, Mastoridis, Sotiris, Merritt, Elliot, Kodela, Elisavet, Yang, Jennie H. M., Danger, Richard, Mairal, Marta, Christakoudi, Sofia, Lozano, Juan J., Macdougall, Iain C., Tree, Timothy I. M., Sanchez-Fueyo, Alberto, Martinez-Llordella, Marc
Argitaratua izan da Proc Natl Acad Sci U S A (2017)

Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2

nork Reading, James L, Vaes, Bart, Hull, Caroline, Sabbah, Shereen, Hayday, Thomas, Wang, Nancy S, DiPiero, Anthony, Lehman, Nicholas A, Taggart, Jen M, Carty, Fiona, English, Karen, Pinxteren, Jef, Deans, Robert, Ting, Anthony E, Tree, Timothy I M
Argitaratua izan da Mol Ther (2015)

Natural variation in IL-2 sensitivity influences regulatory T cell frequency and function in individuals with long-standing type 1 diabetes

nork Yang, Jennie H.M., Cutler, Antony J., Ferreira, Ricardo C., Reading, James L., Cooper, Nicholas J., Wallace, Chris, Clarke, Pamela, Smyth, Deborah J., Boyce, Christopher S., Gao, Guo-Jian, Todd, John A., Wicker, Linda S., Tree, Timothy I.M.
Argitaratua izan da Diabetes (2015)

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

nork Johnson, Matthew B., Patel, Kashyap A., De Franco, Elisa, Hagopian, William, Killian, Michael, McDonald, Timothy J., Tree, Timothy I. M., Domingo-Vila, Clara, Hudson, Michelle, Hammersley, Suzanne, Dobbs, Rebecca, Ellard, Sian, Flanagan, Sarah E., Hattersley, Andrew T., Oram, Richard A.
Argitaratua izan da Diabetologia (2020)

Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer

nork McKenzie, Duncan R., Graham, Rosalind, Lechmere, Thomas, Domingo-Vila, Clara, Alaguthurai, Thanussuyah, Arman, Celeste, Pollock, Emily, Gousis, Charalampos, Kakkassery, Helen, Carpenter, Esme, Kurshan, Ashwini, Vidler, Jennifer, Kulasekararaj, Austin, Patten, Piers, North, Bernard V., Tree, Timothy, Doores, Katie J., Hayday, Adrian C., Irshad, Sheeba
Argitaratua izan da Cancer Res Commun (2022)

CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

nork Skowera, Ania, Ellis, Richard J., Varela-Calviño, Ruben, Arif, Sefina, Huang, Guo Cai, Van-Krinks, Cassie, Zaremba, Anna, Rackham, Chloe, Allen, Jennifer S., Tree, Timothy I.M., Zhao, Min, Dayan, Colin M., Sewell, Andrew K., Unger, Wendy, Drijfhout, Jan W., Ossendorp, Ferry, Roep, Bart O., Peakman, Mark
Argitaratua 2008

CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

nork Skowera, Ania, Ellis, Richard J., Varela-Calviño, Ruben, Arif, Sefina, Huang, Guo Cai, Van-Krinks, Cassie, Zaremba, Anna, Rackham, Chloe, Allen, Jennifer S., Tree, Timothy I.M., Zhao, Min, Dayan, Colin M., Sewell, Andrew K., Unger, Wendy W., Drijfhout, Jan W., Ossendorp, Ferry, Roep, Bart O., Peakman, Mark
Argitaratua 2009