Reconstruction of a pathway of antigen processing and class II MHC peptide capture

Tekijä Moss, Catherine X, Tree, Timothy I, Watts, Colin
Julkaistu 2007

Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?

Tekijä Hull, Caroline M., Peakman, Mark, Tree, Timothy I. M.
Julkaisussa Diabetologia (2017)

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides

Tekijä Ellis, Richard J, Varela-Calvino, Ruben, Tree, Timothy I M, Peakman, Mark
Julkaistu 2005

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

Tekijä Tree, Timothy I.M., Lawson, Jennifer, Edwards, Hannah, Skowera, Ania, Arif, Sefina, Roep, Bart O., Peakman, Mark
Julkaistu 2010

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

Tekijä Arif, Sefina, Tree, Timothy I., Astill, Thomas P., Tremble, Jennifer M., Bishop, Amanda J., Dayan, Colin M., Roep, Bart O., Peakman, Mark
Julkaistu 2004

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Tekijä Ahmed, Simi, Cerosaletti, Karen, James, Eddie, Long, S. Alice, Mannering, Stuart, Speake, Cate, Nakayama, Maki, Tree, Timothy, Roep, Bart O., Herold, Kevan C., Brusko, Todd M.
Julkaisussa Diabetes (2019)

Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner

Tekijä Carty, Fiona, Corbett, Jennifer M., Cunha, João Paulo M. C. M., Reading, James L., Tree, Timothy I. M., Ting, Anthony E., Stubblefield, Samantha R., English, Karen
Julkaisussa Front Immunol (2018)

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects

Tekijä Arif, Sefina, Pujol-Autonell, Irma, Kamra, Yogesh, Williams, Evangelia, Yusuf, Norkhairin, Domingo-Vila, Clara, Shahrabi, Yasaman, Pollock, Emily, Khatri, Leena, Peakman, Mark, Tree, Timothy, Lorenc, Anna
Julkaisussa Front Immunol (2021)

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

Tekijä Allen, Jennifer S., Pang, Karl, Skowera, Ania, Ellis, Richard, Rackham, Chloe, Lozanoska-Ochser, Biliana, Tree, Timothy, Leslie, R. David G., Tremble, Jennifer M., Dayan, Colin M., Peakman, Mark
Julkaistu 2009

GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells

Tekijä Arif, Sefina, Gomez-Tourino, Iria, Kamra, Yogesh, Pujol-Autonell, Irma, Hanton, Emily, Tree, Timothy, Melandri, Daisy, Hull, Caroline, Wherrett, Diane K., Beam, Craig, Roep, Bart O., Lorenc, Anna, Peakman, Mark
Julkaisussa Diabetologia (2020)

Type 1 Diabetes-associated IL2RAvariationlowers IL-2 signaling and contributes to diminished CD4(+)CD25(+) regulatory T-cell function

Tekijä Garg, Garima, Tyler, Jennifer R, Yang, Jennie H M, Cutler, Antony J, Downes, Kate, Pekalski, Marcin, Bell, Louise, Nutland, Sarah, Peakman, Mark, Todd, John A, Wicker, Linda S, Tree, Timothy I M
Julkaistu 2012

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis

Tekijä Lu, Ching-Hua, Allen, Kezia, Oei, Felicia, Leoni, Emanuela, Kuhle, Jens, Tree, Timothy, Fratta, Pietro, Sharma, Nikhil, Sidle, Katie, Howard, Robin, Orrell, Richard, Fish, Mark, Greensmith, Linda, Pearce, Neil, Gallo, Valentina, Malaspina, Andrea
Julkaisussa Neurol Neuroimmunol Neuroinflamm (2016)

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

Tekijä Arif, Sefina, Moore, Fabrice, Marks, Katherine, Bouckenooghe, Thomas, Dayan, Colin M., Planas, Raquel, Vives-Pi, Marta, Powrie, Jake, Tree, Timothy, Marchetti, Piero, Huang, Guo Cai, Gurzov, Esteban N., Pujol-Borrell, Ricardo, Eizirik, Decio L., Peakman, Mark
Julkaistu 2011

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors

Tekijä Whitehouse, Gavin, Gray, Elizabeth, Mastoridis, Sotiris, Merritt, Elliot, Kodela, Elisavet, Yang, Jennie H. M., Danger, Richard, Mairal, Marta, Christakoudi, Sofia, Lozano, Juan J., Macdougall, Iain C., Tree, Timothy I. M., Sanchez-Fueyo, Alberto, Martinez-Llordella, Marc
Julkaisussa Proc Natl Acad Sci U S A (2017)

Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2

Tekijä Reading, James L, Vaes, Bart, Hull, Caroline, Sabbah, Shereen, Hayday, Thomas, Wang, Nancy S, DiPiero, Anthony, Lehman, Nicholas A, Taggart, Jen M, Carty, Fiona, English, Karen, Pinxteren, Jef, Deans, Robert, Ting, Anthony E, Tree, Timothy I M
Julkaisussa Mol Ther (2015)

Natural variation in IL-2 sensitivity influences regulatory T cell frequency and function in individuals with long-standing type 1 diabetes

Tekijä Yang, Jennie H.M., Cutler, Antony J., Ferreira, Ricardo C., Reading, James L., Cooper, Nicholas J., Wallace, Chris, Clarke, Pamela, Smyth, Deborah J., Boyce, Christopher S., Gao, Guo-Jian, Todd, John A., Wicker, Linda S., Tree, Timothy I.M.
Julkaisussa Diabetes (2015)

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

Tekijä Johnson, Matthew B., Patel, Kashyap A., De Franco, Elisa, Hagopian, William, Killian, Michael, McDonald, Timothy J., Tree, Timothy I. M., Domingo-Vila, Clara, Hudson, Michelle, Hammersley, Suzanne, Dobbs, Rebecca, Ellard, Sian, Flanagan, Sarah E., Hattersley, Andrew T., Oram, Richard A.
Julkaisussa Diabetologia (2020)

Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer

Tekijä McKenzie, Duncan R., Graham, Rosalind, Lechmere, Thomas, Domingo-Vila, Clara, Alaguthurai, Thanussuyah, Arman, Celeste, Pollock, Emily, Gousis, Charalampos, Kakkassery, Helen, Carpenter, Esme, Kurshan, Ashwini, Vidler, Jennifer, Kulasekararaj, Austin, Patten, Piers, North, Bernard V., Tree, Timothy, Doores, Katie J., Hayday, Adrian C., Irshad, Sheeba
Julkaisussa Cancer Res Commun (2022)

CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

Tekijä Skowera, Ania, Ellis, Richard J., Varela-Calviño, Ruben, Arif, Sefina, Huang, Guo Cai, Van-Krinks, Cassie, Zaremba, Anna, Rackham, Chloe, Allen, Jennifer S., Tree, Timothy I.M., Zhao, Min, Dayan, Colin M., Sewell, Andrew K., Unger, Wendy, Drijfhout, Jan W., Ossendorp, Ferry, Roep, Bart O., Peakman, Mark
Julkaistu 2008

CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

Tekijä Skowera, Ania, Ellis, Richard J., Varela-Calviño, Ruben, Arif, Sefina, Huang, Guo Cai, Van-Krinks, Cassie, Zaremba, Anna, Rackham, Chloe, Allen, Jennifer S., Tree, Timothy I.M., Zhao, Min, Dayan, Colin M., Sewell, Andrew K., Unger, Wendy W., Drijfhout, Jan W., Ossendorp, Ferry, Roep, Bart O., Peakman, Mark
Julkaistu 2009