Plasma Neurofilament Heavy Chain Levels Correlate to Markers of Late Stage Disease Progression and Treatment Response in SOD1(G93A) Mice that Model ALS

Por Lu, Ching-Hua, Petzold, Axel, Kalmar, Bernadett, Dick, James, Malaspina, Andrea, Greensmith, Linda
Publicado em 2012

The potential of neurofilaments analysis using dry-blood and plasma spots

Por Lombardi, Vittoria, Carassiti, Daniele, Giovannoni, Gavin, Lu, Ching-Hua, Adiutori, Rocco, Malaspina, Andrea
Publicado no Sci Rep (2020)

Author Correction: The potential of neurofilaments analysis using dry-blood and plasma spots

Por Lombardi, Vittoria, Carassiti, Daniele, Giovannoni, Gavin, Lu, Ching-Hua, Adiutori, Rocco, Malaspina, Andrea
Publicado no Sci Rep (2020)

Protein aggregate formation permits millennium-old brain preservation

Por Petzold, Axel, Lu, Ching-Hua, Groves, Mike, Gobom, Johan, Zetterberg, Henrik, Shaw, Gerry, O’Connor, Sonia
Publicado no J R Soc Interface (2020)

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS

Por Menke, Ricarda A L, Gray, Elizabeth, Lu, Ching-Hua, Kuhle, Jens, Talbot, Kevin, Malaspina, Andrea, Turner, Martin R
Publicado no Ann Clin Transl Neurol (2015)

A motor neuron strategy to save time and energy in neurodegeneration: adaptive protein stoichiometry

Por Zucchi, Elisabetta, Lu, Ching‐Hua, Cho, Yunju, Chang, Rakwoo, Adiutori, Rocco, Zubiri, Irene, Ceroni, Mauro, Cereda, Cristina, Pansarasa, Orietta, Greensmith, Linda, Malaspina, Andrea, Petzold, Axel
Publicado no J Neurochem (2018)

Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis

Por Leoni, Emanuela, Bremang, Michael, Mitra, Vikram, Zubiri, Irene, Jung, Stephan, Lu, Ching-Hua, Adiutori, Rocco, Lombardi, Vittoria, Russell, Claire, Koncarevic, Sasa, Ward, Malcolm, Pike, Ian, Malaspina, Andrea
Publicado no Sci Rep (2019)

Author Correction: Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis

Por Leoni, Emanuela, Bremang, Michael, Mitra, Vikram, Zubiri, Irene, Jung, Stephan, Lu, Ching-Hua, Adiutori, Rocco, Lombardi, Vittoria, Russell, Claire, Koncarevic, Sasa, Ward, Malcolm, Pike, Ian, Malaspina, Andrea
Publicado no Sci Rep (2020)

Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis

Por Fratta, Pietro, Charnock, James, Collins, Toby, Devoy, Anny, Howard, Robin, Malaspina, Andrea, Orrell, Richard, Sidle, Katie, Clarke, Jan, Shoai, Maryam, Lu, Ching-hua, Hardy, John, Plagnol, Vincent, Fisher, Elizabeth M C
Publicado em 2014

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis

Por Zubiri, Irene, Lombardi, Vittoria, Bremang, Michael, Mitra, Vikram, Nardo, Giovanni, Adiutori, Rocco, Lu, Ching-Hua, Leoni, Emanuela, Yip, Ping, Yildiz, Ozlem, Ward, Malcolm, Greensmith, Linda, Bendotti, Caterina, Pike, Ian, Malaspina, Andrea
Publicado no Mol Neurodegener (2018)

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis

Por Lu, Ching-Hua, Allen, Kezia, Oei, Felicia, Leoni, Emanuela, Kuhle, Jens, Tree, Timothy, Fratta, Pietro, Sharma, Nikhil, Sidle, Katie, Howard, Robin, Orrell, Richard, Fish, Mark, Greensmith, Linda, Pearce, Neil, Gallo, Valentina, Malaspina, Andrea
Publicado no Neurol Neuroimmunol Neuroinflamm (2016)

Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study

Por Lu, Ching-Hua, Petzold, Axel, Topping, Jo, Allen, Kezia, Macdonald-Wallis, Corrie, Clarke, Jan, Pearce, Neil, Kuhle, Jens, Giovannoni, Gavin, Fratta, Pietro, Sidle, Katie, Fish, Mark, Orrell, Richard, Howard, Robin, Greensmith, Linda, Malaspina, Andrea
Publicado no J Neurol Neurosurg Psychiatry (2015)

Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis

Por Lu, Ching-Hua, Macdonald-Wallis, Corrie, Gray, Elizabeth, Pearce, Neil, Petzold, Axel, Norgren, Niklas, Giovannoni, Gavin, Fratta, Pietro, Sidle, Katie, Fish, Mark, Orrell, Richard, Howard, Robin, Talbot, Kevin, Greensmith, Linda, Kuhle, Jens, Turner, Martin R., Malaspina, Andrea
Publicado no Neurology (2015)

Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy

Por Lombardi, Vittoria, Querin, Giorgia, Ziff, Oliver J., Zampedri, Luca, Martinelli, Ilaria, Heller, Carolin, Foiani, Martha, Bertolin, Cinzia, Lu, Ching-Hua, Malik, Bilal, Allen, Kezia, Rinaldi, Carlo, Zetterberg, Henrik, Heslegrave, Amanda, Greensmith, Linda, Hanna, Michael, Soraru, Gianni, Malaspina, Andrea, Fratta, Pietro
Publicado no Neurology (2019)

CHCHD10 Pro34Ser is not a highly penetrant pathogenic variant for amyotrophic lateral sclerosis and frontotemporal dementia

Por Abdelkarim, Samir, Morgan, Sarah, Plagnol, Vincent, Lu, Ching-Hua, Adamson, Gary, Howard, Robin, Malaspina, Andrea, Orrell, Richard, Sharma, Nikhil, Sidle, Katie, Clarke, Jan, Fox, Nick C., Rossor, Martin N., Warren, Jason D., Clark, Camilla N., Rohrer, Jonathan D., Fisher, Elizabeth M. C., Mead, Simon, Pittman, Alan, Fratta, Pietro
Publicado no Brain (2016)

Targeting Protein Homeostasis in Sporadic Inclusion Body Myositis

Por Ahmed, Mhoriam, Machado, Pedro M., Miller, Adrian, Spicer, Charlotte, Herbelin, Laura, He, Jianghua, Noel, Janelle, Wang, Yunxia, McVey, April L., Pasnoor, Mamatha, Gallagher, Philip, Statland, Jeffrey, Lu, Ching-Hua, Kalmar, Bernadett, Brady, Stefen, Sethi, Huma, Samandouras, George, Parton, Matt, Holton, Janice L., Weston, Anne, Collinson, Lucy, Taylor, J. Paul, Schiavo, Giampietro, Hanna, Michael G., Barohn, Richard J., Dimachkie, Mazen M., Greensmith, Linda
Publicado no Sci Transl Med (2016)

Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion()

Por Fratta, Pietro, Polke, James M., Newcombe, Jia, Mizielinska, Sarah, Lashley, Tammaryn, Poulter, Mark, Beck, Jon, Preza, Elisavet, Devoy, Anny, Sidle, Katie, Howard, Robin, Malaspina, Andrea, Orrell, Richard W., Clarke, Jan, Lu, Ching-Hua, Mok, Kin, Collins, Toby, Shoaii, Maryam, Nanji, Tina, Wray, Selina, Adamson, Gary, Pittman, Alan, Renton, Alan E., Traynor, Bryan J., Sweeney, Mary G., Revesz, Tamas, Houlden, Henry, Mead, Simon, Isaacs, Adrian M., Fisher, Elizabeth M.C.
Publicado no Neurobiol Aging (2015)

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

Por Bridel, Claire, van Wieringen, Wessel N., Zetterberg, Henrik, Tijms, Betty M., Teunissen, Charlotte E., Alvarez-Cermeño, José C., Andreasson, Ulf, Axelsson, Markus, Bäckström, David C., Bartos, Ales, Bjerke, Maria, Blennow, Kaj, Boxer, Adam, Brundin, Lou, Burman, Joachim, Christensen, Tove, Fialová, Lenká, Forsgren, Lars, Frederiksen, Jette L., Gisslén, Magnus, Gray, Elizabeth, Gunnarsson, Martin, Hall, Sara, Hansson, Oskar, Herbert, Megan K., Jakobsson, Joel, Jessen-Krut, Jan, Janelidze, Shorena, Johannsson, Gudmundur, Jonsson, Michael, Kappos, Ludwig, Khademi, Mohsen, Khalil, Michael, Kuhle, Jens, Landén, Mikael, Leinonen, Ville, Logroscino, Giancarlo, Lu, Ching-Hua, Lycke, Jan, Magdalinou, Nadia K., Malaspina, Andrea, Mattsson, Niklas, Meeter, Lieke H., Mehta, Sanjay R., Modvig, Signe, Olsson, Tomas, Paterson, Ross W., Pérez-Santiago, Josué, Piehl, Fredrik, Pijnenburg, Yolande A. L., Pyykkö, Okko T., Ragnarsson, Oskar, Rojas, Julio C., Romme Christensen, Jeppe, Sandberg, Linda, Scherling, Carole S., Schott, Jonathan M., Sellebjerg, Finn T., Simone, Isabella L., Skillbäck, Tobias, Stilund, Morten, Sundström, Peter, Svenningsson, Anders, Tortelli, Rosanna, Tortorella, Carla, Trentini, Alessandro, Troiano, Maria, Turner, Martin R., van Swieten, John C., Vågberg, Mattias, Verbeek, Marcel M., Villar, Luisa M., Visser, Pieter Jelle, Wallin, Anders, Weiss, Andreas, Wikkelsø, Carsten, Wild, Edward J.
Publicado no JAMA Neurol (2019)