CSF neurofilament light chain reflects corticospinal tract degeneration in ALS

OBJECTIVE: Diffusion tensor imaging (DTI) is sensitive to white matter tract pathology. A core signature involving the corticospinal tracts (CSTs) has been identified in amyotrophic lateral sclerosis (ALS). Raised neurofilament light chain protein (NfL) in cerebrospinal fluid (CSF) is thought to ref...

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Dades bibliogràfiques
Publicat a:Ann Clin Transl Neurol
Autors principals: Menke, Ricarda A L, Gray, Elizabeth, Lu, Ching-Hua, Kuhle, Jens, Talbot, Kevin, Malaspina, Andrea, Turner, Martin R
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531057/
https://ncbi.nlm.nih.gov/pubmed/26273687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.212
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