HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides

Enteroviruses such as coxsackievirus B4 (CVB4) are proposed as possible environmental triggers or accelerants of the autoimmune process that leads to type 1 diabetes mellitus. One putative mechanism to account for this association is mimicry between virus components and islet autoantigens. Particula...

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Bibliographic Details
Main Authors: Ellis, Richard J, Varela-Calvino, Ruben, Tree, Timothy I M, Peakman, Mark
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802420/
https://ncbi.nlm.nih.gov/pubmed/16236123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02233.x
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