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Identification of a Naturally Processed Cytotoxic CD8 T-Cell Epitope of Coxsackievirus B4, Presented by HLA-A2.1 and Located in the PEVKEK Region of the P2C Nonstructural Protein

The adaptive immune system generates CD8 cytotoxic T lymphocytes (CTLs) as a major component of the protective response against viruses. Knowledge regarding the nature of the peptide sequences presented by HLA class I molecules and recognized by CTLs is thus important for understanding host-pathogen...

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Detalhes bibliográficos
Main Authors: Varela-Calvino, Ruben, Skowera, Ania, Arif, Sefina, Peakman, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533958/
https://ncbi.nlm.nih.gov/pubmed/15564450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13399-13408.2004
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