Predominance of HLA-Restricted Cytotoxic T-Lymphocyte Responses to Serotype-Cross-Reactive Epitopes on Nonstructural Proteins following Natural Secondary Dengue Virus Infection

We examined the memory cytotoxic T-lymphocytic (CTL) responses of peripheral blood mononuclear cells (PBMC) obtained from patients in Thailand 12 months after natural symptomatic secondary dengue virus infection. In all four patients analyzed, CTLs were detected in bulk culture PBMC against nonstruc...

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Detalhes bibliográficos
Main Authors: Mathew, Anuja, Kurane, Ichiro, Green, Sharone, Stephens, Henry A. F., Vaughn, David W., Kalayanarooj, Siripen, Suntayakorn, Saroj, Chandanayingyong, Dasnayanee, Ennis, Francis A., Rothman, Alan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109627/
https://ncbi.nlm.nih.gov/pubmed/9557687
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