Predominance of HLA-Restricted Cytotoxic T-Lymphocyte Responses to Serotype-Cross-Reactive Epitopes on Nonstructural Proteins following Natural Secondary Dengue Virus Infection

We examined the memory cytotoxic T-lymphocytic (CTL) responses of peripheral blood mononuclear cells (PBMC) obtained from patients in Thailand 12 months after natural symptomatic secondary dengue virus infection. In all four patients analyzed, CTLs were detected in bulk culture PBMC against nonstruc...

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Bibliographische Detailangaben
Hauptverfasser: Mathew, Anuja, Kurane, Ichiro, Green, Sharone, Stephens, Henry A. F., Vaughn, David W., Kalayanarooj, Siripen, Suntayakorn, Saroj, Chandanayingyong, Dasnayanee, Ennis, Francis A., Rothman, Alan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Viral Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109627/
https://ncbi.nlm.nih.gov/pubmed/9557687
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