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Reconstruction of a pathway of antigen processing and class II MHC peptide capture

Endocytosed antigens are proteolytically processed and small amounts of peptides captured by class II MHC molecules. The details of antigen proteolysis, peptide capture and how destruction of T-cell epitopes is avoided are incompletely understood. Using the tetanus toxin antigen, we show that the in...

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Detalhes bibliográficos
Main Authors: Moss, Catherine X, Tree, Timothy I, Watts, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852786/
https://ncbi.nlm.nih.gov/pubmed/17396153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601660
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