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Reconstruction of a pathway of antigen processing and class II MHC peptide capture

Endocytosed antigens are proteolytically processed and small amounts of peptides captured by class II MHC molecules. The details of antigen proteolysis, peptide capture and how destruction of T-cell epitopes is avoided are incompletely understood. Using the tetanus toxin antigen, we show that the in...

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Detalles Bibliográficos
Main Authors: Moss, Catherine X, Tree, Timothy I, Watts, Colin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852786/
https://ncbi.nlm.nih.gov/pubmed/17396153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601660
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