Distinct antigen MHC class II complexes generated by separate processing pathways.

The peptide binding site of MHC class II molecules is open at both ends and, therefore, does not restrict the length of the bound ligand. Here we show that a partially folded protein antigen (*HEL) spontaneously formed SDS-unstable complexes with the purified MHC class II molecule I-Ak (Ak). These c...

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Bibliographic Details
Main Authors: Lindner, R, Unanue, E R
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452517/
https://ncbi.nlm.nih.gov/pubmed/9003767
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