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The Mechanism of HLA-DM Induced Peptide Exchange in the MHC class II Antigen Presentation Pathway
HLA-DM serves a critical function in the loading and editing of peptides on MHC class II molecules. Recent data showed that the interaction cycle between MHC class II molecules and HLA-DM is dependent on the occupancy state of the peptide binding groove. Empty MHC class II molecules form stable comp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288754/ https://ncbi.nlm.nih.gov/pubmed/22138314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.11.004 |
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