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Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange

Antigen presentation by class II MHC proteins (MHC-II) is a critical component of the adaptive immune response to foreign pathogens. Our understanding of how antigens are presented has been greatly enhanced by crystallographic studies of MHC-II-peptide complexes, which have shown a canonical extende...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Painter, Corrie A., Stern, Lawrence J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175922/
https://ncbi.nlm.nih.gov/pubmed/25264402
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