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HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation
Peptide loading of class II MHC molecules in endosomal compartments is regulated by HLA-DM. HLA-DO modulates HLA-DM function, with consequences for the spectrum of MHC-bound epitopes presented at the cell surface for interaction with T cells. Here, we summarize and discuss recent progress in investi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944065/ https://ncbi.nlm.nih.gov/pubmed/24463216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.11.005 |
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