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The MHC class II cofactor, HLA-DM, interacts with immunoglobulin in B cells
B cells internalize extracellular antigen into endosomes using the immunoglobulin (Ig) component of the B cell receptor. In endosomes, antigen-derived peptides are loaded onto MHC class II proteins (MHC-II). How these pathways intersect remains unclear. We find that HLA-DM (DM), a catalyst for MHC-I...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157100/ https://ncbi.nlm.nih.gov/pubmed/25098292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400075 |
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