The MHC class II cofactor, HLA-DM, interacts with immunoglobulin in B cells

B cells internalize extracellular antigen into endosomes using the immunoglobulin (Ig) component of the B cell receptor. In endosomes, antigen-derived peptides are loaded onto MHC class II proteins (MHC-II). How these pathways intersect remains unclear. We find that HLA-DM (DM), a catalyst for MHC-I...

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Detaylı Bibliyografya
Asıl Yazarlar: Macmillan, Henriette, Strohman, Michael J., Ayyangar, Sashi, Jiang, Wei, Rajasekaran, Narendiran, Spura, Armin, Hessell, Ann J., Madec, Anne-Marie, Mellins, Elizabeth D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157100/
https://ncbi.nlm.nih.gov/pubmed/25098292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400075
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