Inhibition of HLA-DM Mediated MHC Class II Peptide Loading by HLA-DO Promotes Self Tolerance

Eitemau Tebyg

• A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.
  gan: Kropshofer, H, et al.
  Cyhoeddwyd: (1998)
• HLA-DM catalytically enhances peptide dissociation by sensing peptide–MHC class II interactions throughout the peptide-binding cleft
  gan: Reyes-Vargas, Eduardo, et al.
  Cyhoeddwyd: (2020)
• The Thermodynamic Mechanism of Peptide–MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM
  gan: Ferrante, Andrea, et al.
  Cyhoeddwyd: (2015)
• The Mechanism of HLA-DM Induced Peptide Exchange in the MHC class II Antigen Presentation Pathway
  gan: Schulze, Monika-Sarah E. D., et al.
  Cyhoeddwyd: (2011)
• Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange
  gan: Painter, Corrie A., et al.
  Cyhoeddwyd: (2011)