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The Thermodynamic Mechanism of Peptide–MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM

Peptides bind MHC class II molecules through a thermodynamically nonadditive process consequent to the flexibility of the reactants. Currently, how the specific outcome of this binding process affects the ensuing epitope selection needs resolution. Calorimetric assessment of binding thermodynamics f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Ferrante, Andrea, Templeton, Megan, Hoffman, Megan, Castellini, Margaret J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: AAI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505951/
https://ncbi.nlm.nih.gov/pubmed/26116504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402367
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