A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.

In B cells, the non-classical human leukocyte antigens HLA-DO (DO) and HLA-DM (DM) are residents of lysosome-like organelles where they form tight complexes. DM catalyzes the removal of invariant chain-derived CLIP peptides from classical major histocompatibility complex (MHC) class II molecules, ch...

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Detalhes bibliográficos
Main Authors: Kropshofer, H, Vogt, A B, Thery, C, Armandola, E A, Li, B C, Moldenhauer, G, Amigorena, S, Hämmerling, G J
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170637/
https://ncbi.nlm.nih.gov/pubmed/9606180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.11.2971
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