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HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation

Peptide loading of class II MHC molecules in endosomal compartments is regulated by HLA-DM. HLA-DO modulates HLA-DM function, with consequences for the spectrum of MHC-bound epitopes presented at the cell surface for interaction with T cells. Here, we summarize and discuss recent progress in investi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mellins, Elizabeth D., Stern, Lawrence J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944065/
https://ncbi.nlm.nih.gov/pubmed/24463216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.11.005
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